DR.MESO® Collagène Peptide Boosting Serum for dry and mature skin
DR.MESO® Collagène Peptide Boosting Serum lightweight texture
DR.MESO Collagène routine for dry, mature and sensitive-feeling skin
DR.MESO Collagène Peptide Boosting Serum lightweight texture for dry mature skin
Woman applying DR.MESO Collagène skincare with Peptide Boosting Serum
DR.MESO Collagène Peptide Boosting Serum on white background
DR.MESO® Collagène Hydrating Night Gel for overnight moisture care
DR.MESO® Collagène Peptide Boosting Serum for dry and mature skin
DR.MESO® Collagène Peptide Boosting Serum lightweight texture
DR.MESO Collagène routine for dry, mature and sensitive-feeling skin
DR.MESO Collagène Peptide Boosting Serum lightweight texture for dry mature skin
Woman applying DR.MESO Collagène skincare with Peptide Boosting Serum
DR.MESO Collagène Peptide Boosting Serum on white background
DR.MESO® Collagène Hydrating Night Gel for overnight moisture care

Collagen Peptide Serum for Firmness, Fine Lines & Mature Skin | DR.MESO®

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$70.00 CAD

Intensive Peptide Moisture Seal for Very Dry & Dehydrated Skin

DR.MESO® Collagène Peptide Boosting Serum is a unique moisture-sealing peptide serum for very dry, dehydrated and sensitive-feeling skin. It is especially useful during winter, cold weather and dry indoor heating, when skin can quickly lose moisture and feel tight or uncomfortable.

With Palmitoyl Tripeptide-29 and hydrating, skin-conditioning ingredients, this serum is designed to be used differently from a traditional serum: when extra protection from moisture loss is needed, apply it on top of your moisturizer as the final moisture-sealing layer. Think of it as a lightweight “winter coat” over your skincare routine.

Why Tripeptide-29 Matters

Palmitoyl Tripeptide-29 is a cosmetic peptide used to support smoother, firmer-looking skin. Combined with the serum’s moisture-sealing formula, it helps support softness, comfort and a supple-looking complexion when skin feels extremely dry or dehydrated.

Key Benefits

  • Creates a lightweight moisture-sealing layer over moisturizer
  • Helps reduce moisture loss and the feeling of dryness and tightness
  • Supports softer, smoother and more supple-looking skin
  • Ideal for very dry and dehydrated skin
  • Useful during cold, windy winter weather and dry indoor heating
  • Can be used on face and very dry areas of the body
  • Suitable for adults and teenagers experiencing very dry or dehydrated skin
  • Made in Canada

Key Ingredients

Palmitoyl Tripeptide-29 — a cosmetic peptide that helps support smoother, firmer-looking skin and complements the serum’s intensive moisture-sealing care.

Hydrolyzed Elastin — helps condition the skin and support a soft, supple feel.

Avocado Oil — an emollient oil that helps soften and condition dry skin.

Glycerin — a humectant that helps attract moisture and support skin hydration.

Castor Seed Oil — helps condition skin and support the formula’s moisture-sealing feel.

Palmitoyl Silk Amino Acid — helps condition the skin and support a smooth feel.

Winter & Outdoor Skin Care

Cold air, wind and dry conditions can leave exposed skin feeling dry, tight and uncomfortable. Before winter walks, skiing, skating or other outdoor activities, apply your regular face or body moisturizer first, then layer Collagène Peptide Boosting Serum on top as a moisture-sealing layer. It helps reduce moisture loss and keeps skin feeling softer and more comfortable in cold-weather conditions.

For Very Dry Body Skin

Use on very dry, dehydrated areas such as the hands, arms and legs. After showering, apply your regular body cream first, then smooth a small amount of the serum on top as the final moisture-sealing layer. This combination is especially useful during winter when skin is exposed to cold outdoor air and dry indoor heating.

For Best Results

Cream first → Peptide Boosting Serum on top. Use as the final moisture-sealing step whenever skin needs extra comfort and hydration support.

How to Use

  1. Apply your regular DR.MESO® moisturizer or body cream first.
  2. Smooth a small amount of Collagène Peptide Boosting Serum over the cream as the final moisture-sealing layer.
  3. For the face, apply over face and neck and avoid the eye area.
  4. For the body, focus on very dry areas such as hands, arms and legs.
  5. Use morning and/or evening as needed, especially during winter, cold weather, outdoor activities or periods of very dry, dehydrated skin.

Frequently Asked Questions

Is this a traditional serum step?
When extra moisture-seal support is needed, this serum is designed to be layered on top of moisturizer rather than underneath it.

Can teenagers use it?
It can be used by adults and teenagers when skin is very dry or dehydrated. For younger children or persistent skin problems, consult an appropriate healthcare professional.

Can I use it on my body?
Yes. Apply body cream first, then layer the serum over very dry areas such as hands, arms or legs.

Is it useful for winter sports?
It can be used as a moisture-sealing skincare layer before outdoor winter activities to help reduce moisture loss and keep skin feeling comfortable.

Made in Canada.

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COMPLETE YOUR SKIN ROUTINE
Woman rinsing face after using Dr. Meso cleanser
Step 1

Wash face with Collagene Cleansing Lotion

Woman applying Dr Meso with sponge
Step 2

Apply Collagene Toner with cotton swab or sponge.

Woman using Dr. Meso cleanser on face
Step 3

Apply Collagene Day Cream

Woman's face with Dr Meso cream dabbed on cheek
Step 4

Apply Collagene Boosting Serum, on top of Day Cream.
Customers rate us 5.0/5 based on 74 reviews.

Let customers speak for us

from 74 reviews

As a man, I really liked their hair products and face cream from the collagen line. The cream has nice texture and good moisturising
With shampoo my hair was fresh longer.

RedDragon Emil

I started using their hair care line for PCOS-related hair loss on my ND’s recommendation. Their shampoo, conditioner and hair mask really helped to reduce hair fall in the shower. I didn’t notice as much new growth though. I had to combine other methods with their products to see new hair growth (minoxidil, dermarolling, and rosemary water to name a few). Overall, very happy with how clean and effective their products are!

Tharshni Velauthapillai

I'm in love with the whole line... The peel is absolutely fantastic... I work at a hair school and medical aesthetic school
I love this product so much I'm hoping to carry it with our school

Kimberly M

I purchased the face mask, oily-free line for my family. The entire system works well(We've used the entire line before). I'm trying their other skincare products, I'll let you know the progress.

There SheGrows

I am so happy that Dr. Meso exists! I am a Transcendental Intuitive Healer and former aesthetician and was looking for Europian wisdom purity in self-care products that would be Canadian, Organic, Homeopathic with supplements and prices that are moderate for the quality it brings. Easy protocols and deep penetration of fine formular - I just LOVE it! Well thought!

Sonja

Great products! Great service! I've been a customer for a long time. Very happy about the results.

Ludmyla Koel

Been using Mr. Meso products for over two years now. Love the fact that they are made in Canada. After regular use, my skin is glowing and completely acne free. As of today, my favorite go to are detox mask and collagen night cream.

Maria Rastoropina

Last week I went for a skin treatment and was recommended the Liftox Cream by Dr. Mezo. I was impressed by the effect of this cream. It provides supreme toning, lifting, and moisture to my dull saggy skin. In addition, it comes in a box with a pleasant soft touch. I could not believe that it was made of recycled paper. It was very easy to take the jar out of this nice double wall box. The jar itself is so beautiful, like a jewel. It has a pump which makes it very convenient to get the cream without sticking my fingers into the jar. I would highly recommend this product if you like to get a good cosmetic effect and aesthetic pleasure.

Natalia “Natalka M” M

The Dr. Meso acne free cleanser and toner have helped clear my acne and control my oily skin without drying it out! The cleanser is very gentle, yet effective and the toner is very refreshing! Liliana was very helpful in suggesting products and offering knowledgable advice. Can't wait to try other products in the acne free line!

Kylie Johnston

Best quality products and prices are great!! I'm all acne-free now!

Danylo Dutka