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Collagene Retinol Serum bottle next to a person with glowing, healthy skin.
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triple action retinol collagen night gel for smoother clear skin
retinol collagen gel night moisturizer canada gentle resurfacing.
lightweight retinol night gel for acne prone adult skin
Collagene Retinol Serum bottle next to a person with glowing, healthy skin.
collagen retinol hydrating gel for dull uneven texture
Acne scars and pigmentation treatment results with Chameleon Peel.

TRIPLE ACTION RETINOL COMPLEX NIGHT SERUM - COLLAGENE

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$110.00 CAD

DR.MESO® Triple Action Retinol Night Serum — Collagen-Supporting Night Renewal

DR.MESO® Triple Action Retinol Night Serum is a gentle, routine-friendly evening serum that supports smoother-looking texture, youthful-looking radiance and refined skin appearance over time. Formulated with encapsulated retinol, retinaldehyde and collagen-supporting peptides, this lightweight night serum helps maintain suppleness while remaining suitable for dry, sensitive-prone and mature skin.

Why this serum works

  • Supports smoother-looking texture and refined appearance
  • Helps maintain a youthful-looking glow over time
  • Hydration support through hyaluronic acid and niacinamide
  • Collagen-friendly peptides for a supple, radiant feel
  • Routine-friendly for sensitive-prone and mature skin

Triple Action Formula

  • Encapsulated Retinol: gradual nightly renewal for a smoother look
  • Retinal (Retinaldehyde): supports refined, even-looking texture
  • Tripeptide-29: collagen-supporting peptide for a supple appearance

Support ingredients

  • Niacinamide: balances tone appearance and comforts sensitive-prone skin
  • Vitamin E: antioxidant support for a radiant finish
  • Hyaluronic Acid: lightweight hydration that feels smooth, not heavy

How to use

PM only: Cleanser → Toner → Retinol Serum → Cream
Start 2–3 nights per week, increase as tolerated.
Avoid eye area. SPF daily.

Who it's for

  • Dry, dehydrated or mature skin
  • Sensitive-prone skin needing balanced retinol support
  • Uneven surface or dull-looking appearance
  • Those beginning or maintaining an evening renewal routine

Professional note

Can be combined with controlled exfoliation and microneedling routines when sequenced by trained professionals. Protocols and online training available upon registration for licensed providers.

Packaging

30 ml airless pump supports freshness, hygiene and ingredient stability.

DR.MESO® Brand

Clean Canadian skincare • routine-friendly formulas • pharmaceutical-grade process • no parabens • airless recyclable packaging • trusted by clinics • made in Canada

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COMPLETE YOUR SKIN ROUTINE
Step 1

Wash face with Collagene Cleansisng Lotion

Step 2

Apply Collagene Toner with cotton swab or sponge

Step 3

Apply Collagene Triple Action Retinol Serum at night time before bed

Step 4

For best results, apply Collagene Night Gel at night time before bed on top of Retinol Serum
Customers rate us 5.0/5 based on 43 reviews.

Let customers speak for us

from 43 reviews

As a man, I really liked their hair products and face cream from the collagen line. The cream has nice texture and good moisturising
With shampoo my hair was fresh longer.

RedDragon Emil
DR.MESO

I started using their hair care line for PCOS-related hair loss on my ND’s recommendation. Their shampoo, conditioner and hair mask really helped to reduce hair fall in the shower. I didn’t notice as much new growth though. I had to combine other methods with their products to see new hair growth (minoxidil, dermarolling, and rosemary water to name a few). Overall, very happy with how clean and effective their products are!

Tharshni Velauthapillai
DR.MESO

I'm in love with the whole line... The peel is absolutely fantastic... I work at a hair school and medical aesthetic school
I love this product so much I'm hoping to carry it with our school

Kimberly M
DR.MESO

I purchased the face mask, oily-free line for my family. The entire system works well(We've used the entire line before). I'm trying their other skincare products, I'll let you know the progress.

There SheGrows
DR.MESO

I am so happy that Dr. Meso exists! I am a Transcendental Intuitive Healer and former aesthetician and was looking for Europian wisdom purity in self-care products that would be Canadian, Organic, Homeopathic with supplements and prices that are moderate for the quality it brings. Easy protocols and deep penetration of fine formular - I just LOVE it! Well thought!

Sonja
DR.MESO

Great products! Great service! I've been a customer for a long time. Very happy about the results.

Ludmyla Koel
DR.MESO

Been using Mr. Meso products for over two years now. Love the fact that they are made in Canada. After regular use, my skin is glowing and completely acne free. As of today, my favorite go to are detox mask and collagen night cream.

Maria Rastoropina
DR.MESO

Last week I went for a skin treatment and was recommended the Liftox Cream by Dr. Mezo. I was impressed by the effect of this cream. It provides supreme toning, lifting, and moisture to my dull saggy skin. In addition, it comes in a box with a pleasant soft touch. I could not believe that it was made of recycled paper. It was very easy to take the jar out of this nice double wall box. The jar itself is so beautiful, like a jewel. It has a pump which makes it very convenient to get the cream without sticking my fingers into the jar. I would highly recommend this product if you like to get a good cosmetic effect and aesthetic pleasure.

Natalia “Natalka M” M
DR.MESO

The Dr. Meso acne free cleanser and toner have helped clear my acne and control my oily skin without drying it out! The cleanser is very gentle, yet effective and the toner is very refreshing! Liliana was very helpful in suggesting products and offering knowledgable advice. Can't wait to try other products in the acne free line!

Kylie Johnston
DR.MESO

Best quality products and prices are great!! I'm all acne-free now!

Danylo Dutka
DR.MESO